Fumonisin Toxicity in Broiler Chicks

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Involvement of oxidative stress in subacute toxicity induced by fumonisin B1 in broiler chicks.

Fumonisin B1 (FB1) is a mycotoxin produced by Fusarium spp. It has been reported to be a potential cause of liver cancer in rats and esophageal cancer in humans. The underlying mechanisms of FB1 toxicity are thought to be related to the inhibition of ceramide synthase, causing an accumulation of sphingosine (SO) and sphinganine (SA), which in turn may cause tissue functional impairment and the ...

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The dietary use of 0.25% Myco-Ad has been proven to effectively prevent the toxic effects of aflatoxin, ochratoxin and T-2 toxin in broilers. Studies were conducted to evaluate the fumonisin (FUM) adsorption capacity of Myco-Ad and its efficacy in preventing the deleterious effects of high levels of FUM in broiler chicks; as part of the regulatory anti-mycotoxin additives (AMA) approval process...

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Effects of fumonisin B1 on selected immune responses in broiler chicks.

Three experiments were conducted to evaluate immune responses in chicks fed fumonisin B1 (FB1). Day-old male chicks were randomly allotted to dietary treatments: 0, 50, 100, or 200 mg FB1/kg diet. In Experiment 1, chicks were fed diets for 3 wk and were injected intravenously with 4.6x10(6) Escherichia coli on Day 21. Blood samples were collected at 60, 120, and 180 min postinjection, and liver...

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The efficacy of various additives to reduce the toxicity of aflatoxin B1 in broiler chicks

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ژورنال

عنوان ژورنال: Journal of Veterinary Diagnostic Investigation

سال: 1992

ISSN: 1040-6387,1943-4936

DOI: 10.1177/104063879200400317